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The goal of the Nemonic Project (Next generation Multiphoton Neuroimaging Consortium) is to develop and widely disseminate state-of-the-art technology for multiphoton imaging and associated techniques to the neuroscience community, and to advance emerging technology for future innovation in multiphoton neuroimaging. Ultimately, the activities of the Nemonic project will enable new experiments and accelerate discoveries in neuroscience.
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Project Overview
The Nemonic project has three parts. First, there is a development component, called DEV, to create new technology to overcome critical barrier to progress in neuroscience. In a series of Case Studies, neuroengineers will develop custom instrumentation to enable currently impossible neuroscience experiments. A proven work flow involving custom optics and iterative refinement, and culminating in commercially produced parts, will be used to create the custom instrumentation. The Case Studies involve a range of animal models (mice, ferrets, cats, and monkeys), and optical and instrumental challenges.
Second, there is a dissemination component, called DISSEM, to spread this technology broadly to other labs. All engineering materials and resources generated in the Case Studies will be open-sourced and released to the broader public in thoroughly documented and curated web resource. Components and systems developed in the Case Studies will be made commercially available. Also, a series of workshops are held to train scientists on how to design and build custom systems for multiphoton neuroimaging.
Third, there is an advancement component, called ADV, to push the technology of multiphoton neuroimaging into the next frontier. Two technologies will be pursued: miniaturized, highly integrated photonic systems for practical and scalable head-mounted multiphoton neuroimaging in freely moving animals; and superresolution imaging to resolve structures relevant to synaptic and molecular dynamics in vivo. A series of meetings with top names in the field are held to promote novel collaborations and more rapidly advance technologies that are relevant to multiphoton neuroimaging in the future.
For a more in depth description go to Project Details
People
Postdoc: Riichiro Hira, UC Santa Barbara
Postdoc: Chao Liu, UC Santa Barbara
Postdoc: Songtao Liu, UC Santa Barbara
Postdoc: Vijay Namboodiri, University of Washingoton
Optical Engineer: Deano Fairinella, University of Minnesota
Technician: William Nash, Johns Hopkins University
Technician: William Quinlan, Johns Hopkins University
Technician: James Garmon, Johns Hopkins University
Technician: Justin Killebrew, Johns Hopkins University
Experimentalist: Arani Roy, University of Minnesota
Staff Scientist: Prassana Srinivasan, UC Santa Barbara
Staff Scientist: Charles Zhao, University of Washington
Graduate Student: Thomas Burnett, Johns Hopkins University
Graduate Student: Erika Dunn-Weiss, Johns Hopkins University
Graduate Student: Joshua Ross, Johns Hopkins University
Graduate Student: Qingyang Wang, Johns Hopkins University
Graduate Student: Jaden Davidson, Colorado School of Mines
Graduate Student: Alyssa Allende Motz, Colorado School of Mines
Graduate Student: Daniel Scarborough, Colorado School of Mines
Graduate Student: Nathan Worts, Colorado School of Mines
Graduate Student: Mario Dumont, UC Santa Barbara
Graduate Student: Zachary Nelson, UC Santa Barbara
Graduate Student: Rebecca Martin, UC Santa Barbara
Graduate Student: Alexian Nguyen-Le, UC Santa Barbara
Graduate Student: William Redman, UC Santa Barbara
Graduate Student: William Whitehead, UC Santa Barbara
Graduate Student: Madelyn Gray, University of Washington
Research Assistant: Ofelia Garalde, Johns Hopkins University
Research Assistant: Sihao Lu, UC Santa Barbara
Research Assistant: Tyler Marks, UC Santa Barbara
Undergraduate Student: Nigel Bess, UC Santa Barbara
Undergraduate Student: Nicolai Bessera, UC Santa Barbara
Undergraduate Student: Aniket Bhalerao, UC Santa Barbara
Undergraduate Student: Ron Broner, UC Santa Barbara
Undergraduate Student: Derek Flores, UC Santa Barbara
Undergraduate Student: Mark Gepigon, UC Santa Barbara
Undergraduate Student: Cher Lin, UC Santa Barbara
Undergraduate Student: Adel Semma, UC Santa Barbara
Undergraduate Student: Justin Tjoa, UC Santa Barbara
Undergraduate Student: Anthony Simons, University of Minnesota
Funding
The Nemonic project is funded through a National Science Foundation NeuroNex (Next Generation Networks for Neuroscience) award.
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1934288
See Also
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